Moto salamander wakhala akuti ndi nyama zachinsinsi komanso zoopsa. Kuphatikiza pa chikhulupiriro chofala choti akhoza kukhala ndi moto osadzivulaza, zakumwa zake zoopsa zimadziwikanso. Pliny Mkulu (23-79 AD) analemba kuti: "Zoyipa kwambiri kuposa nyama zonse ndi salamander. Ena amaluma anthu osapha ambiri nthawi imodzi. Ndipo salamander atha kuwononga dziko lonse kuti pasawone wina. komwe tsoka limachokera. Ngati salamander atakwera mtengo, zipatso zonse pamtengowo zimakhala zowopsa. nawonso? :) Dziwani Bufo-do.) Ngati agwira gawo lililonse la thupi, kugulitsa mpaka pachala chala, tsitsi lonse lathunthu limatuluka. Komabe, nyama zina, monga nkhumba, zimadya nyama yoopsa chifukwa tonse tili ndi adani. "
Popeza tidapereka msonkho kwa Pliny (ndizovuta kuvomereza zolemba zake), tilingalira momwe chirombo choyipa chikuchitira pakadali pano, pomwe ofufuzawo adachiyesa mozama, osawopa ngakhale tsitsi lonse litayika.
Kufika zaka za 1860, zidapezeka kuti ma alkaloids ndi omwe amagwiritsa ntchito poizoni wa salamander, ndipo mu 1930 mawonekedwe awo a steroid adatsimikizika. Mwamwayi kwa ofufuza ndi ma salamanders, ma alkaloids ochulukirapo atha kupezeka kuchokera ku zotulutsa za parotid za amphibians izi, mosiyana ndi, mwachitsanzo, okwera nkhuni (Dendrobates), zomwe tidalemba kale m'nkhani yathu yapitayi. Alkaloid wamkulu amatchedwa samandarin, ndipo ma alkaloid onse 9 okhala ndi mapangidwe ofanana adasiyanitsidwa. Mtundu wa ma alkaloids ambiri a samandarin ndi kukhalapo kwa mphete ya oxazolidine.
Samandarin ndi woopsa, mlingo wake wowopsa wa mbewa umakhala pafupifupi 70 mcg. Ndi gawo la gulu la neurotoxins ndipo limayambitsa kugwidwa, kupuma, mtima. Kuchokera pamalingaliro azachipatala, ma samandarins amawonedwa ngati opangitsanso mankhwala am'deralo. Kuphatikiza apo, ali ndi zochita zothandizira.
